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Atherosclerosis

Atherosclerosis is a medical condition characterized by the narrowing or blockage of arteries responsible for delivering oxygen-rich blood to the body’s organs. This condition develops over years due to the accumulation of fats, cholesterol, and other substances in the arterial walls, which impedes blood flow to the body’s tissues.

Causes of Atherosclerosis

The following are common causes and risk factors for developing atherosclerosis:

  • High levels of LDL cholesterol (bad cholesterol) and triglycerides in the blood.
  • Smoking.
  • High blood pressure (hypertension).
  • Diabetes.
  • Family history of cardiovascular diseases.
  • Aging.
  • Physical inactivity.
  • Consuming a diet high in fats, salt, and sugar.

Atherosclerosis Symptoms

In its early stages, atherosclerosis often does not present noticeable symptoms. However, as the condition progresses and arteries become significantly narrowed, symptoms may appear depending on the affected artery, as following:

The Heart:

When it affects the heart, it can lead to coronary artery disease (CAD), which may cause:

  • Shortness of breath.
  • Chest pain (angina).
  • Pain in the back, neck, arms, or abdomen.
  • Heart palpitations.
  • Dizziness.
  • Fatigue.
  • Nausea, vomiting, or indigestion.

The Digestive System:

When atherosclerosis affects blood flow to the gastrointestinal tract, it may cause mesenteric ischemia, leading to:

  • Abdominal pain or cramping after eating.
  • Bloating, nausea, or vomiting.
  • Diarrhea.
  • Unintentional weight loss due to fear of pain after meals.

The Legs and feet:

Peripheral artery disease (PAD) can result from impaired blood flow to the legs and feet, leading to:

  • Muscle pain.
  • Burning pain in the feet and toes during rest.
  • Skin color changes, such as redness.
  • Non-healing sores on the feet and toes.

The Kidneys:

Narrowing of the renal arteries may cause:

  • Significantly high blood pressure unresponsive to treatment.
  • Fatigue and exhaustion.
  • Headaches.
  • Unexplained weight loss.
  • Nausea, vomiting, or loss of appetite.
  • Dry skin.
  • Numbness or skin itching.

The Brain:

When blood flow to the brain is reduced, carotid artery disease may develop, presenting symptoms such as:

  • Dizziness.
  • Weakness or loss of sensation on one side of the body.
  • Severe headache.
  • Slurred speech.
  • Vision loss in one eye.

Diagnosis of Atherosclerosis

The diagnosis is based on the patient’s symptoms and medical history. Additional tests to confirm atherosclerosis may include:

  1. Blood Tests: Assess levels of cholesterol, triglycerides, and glucose.
  2. Angiography: Uses special X-rays and contrast dye to visualize and measure blockages.
  3. Ankle-Brachial Index (ABI): Compares blood pressure in the ankle and arm to detect peripheral artery disease.
  4. CT Scan: Helps identify narrow or blocked arteries in the body.
  5. Cardiac MRI: Detects issues related to blood flow within the arteries.
  6. Echocardiogram: Uses ultrasound to image the heart’s chambers and valves and evaluate cardiac function.
  7. Electrocardiogram (ECG): Measures the heart’s electrical activity and rhythm.

Atherosclerosis Treatment

Treatment aims to alleviate symptoms, improve blood flow, and prevent complications like heart attack or stroke. Options include:

Lifestyle Changes

Adopting healthier habits is crucial to slowing the progression of atherosclerosis:

  • Quitting smoking.
  • Regular exercise.
  • Avoiding foods high in fat, salt, and sugar.

Medications

Doctors may prescribe medications to manage atherosclerosis risk factors, such as:

  • Cholesterol-lowering drugs.
  • Antihypertensives.
  • Blood thinners to prevent clots.
  • Medications for blood sugar control.

Medical Procedures and Surgery

In severe cases, procedures may be necessary to restore blood flow, including:

  1. Angioplasty and Stenting: A minimally invasive procedure where a catheter is guided to the narrowed artery. A small balloon is inflated to widen the artery, and a stent may be placed to keep it open.
  2. Endarterectomy: A surgical procedure to remove plaque buildup from the artery walls. When performed on neck arteries, it is known as carotid endarterectomy.
  3. Coronary Artery Bypass Grafting (CABG): Open-heart surgery where a healthy blood vessel is taken from another part of the body to bypass a blocked coronary artery, ensuring proper blood flow to the heart.

Conclusion

Atherosclerosis is a serious medical condition that develops gradually over many years. Preventive measures such as adopting a healthy lifestyle and regular medical check-ups are essential, especially for individuals with risk factors. Early detection and intervention can significantly reduce the risk of life-threatening complications.

https://my.clevelandclinic.org/health/diseases/16753-atherosclerosis-arterial-disease

https://www.mayoclinic.org/diseases-conditions/arteriosclerosis-atherosclerosis/symptoms-causes/syc-20350569

https://www.nhs.uk/conditions/atherosclerosis

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